Opportunity Information: Apply for RFA CK 20 003
Modeling Infectious Diseases in Healthcare Research Projects to Improve Prevention Research and Healthcare Delivery (MInD Healthcare) is a CDC funding opportunity designed to strengthen the way the United States anticipates, understands, and prevents healthcare-associated infections (HAIs), including infections linked to antimicrobial resistance (AR). The central goal is to fund innovative research that builds and applies computational and mathematical modeling approaches that can realistically represent how HAI-causing pathogens spread within and across healthcare settings. These models are expected to go beyond academic exercises by being developed with practical end users in mind, such as researchers, policymakers, and public health professionals who need reliable tools to guide decisions about prevention and response in real healthcare environments.
The NOFO emphasizes three main research aims. First, it supports the development and refinement of models that capture transmission dynamics of pathogens responsible for HAIs, including those that are antimicrobial resistant. This can include modeling spread within hospitals, long-term care facilities, outpatient settings, or networks of facilities where patient movement and shared resources can influence transmission. Second, it prioritizes predictive work that can identify or forecast outbreaks and project trends in the burden of both resistant and susceptible HAIs. In practice, this means using data-informed approaches to anticipate where and when infections may surge, and estimating how the overall HAI landscape might change under different conditions, such as shifts in antibiotic use patterns or infection control practices. Third, it funds studies that use models to evaluate intervention strategies, helping decision-makers compare the likely effectiveness of prevention and control measures, including infection prevention protocols, screening strategies, isolation approaches, environmental cleaning methods, antimicrobial stewardship interventions, or broader system-level policies.
A defining feature of MInD Healthcare is that it is structured to create a connected community of experts focused on HAI and AR modeling. The program is intended to build a network of leading modelers who can collectively serve as a national resource for evidence-based policy development and can also respond to evolving public health needs, including emergencies that arise in healthcare settings. In other words, the CDC is not only funding individual research projects, but also aiming to cultivate an ongoing, coordinated modeling capacity that can be mobilized when new threats or urgent questions emerge.
Administratively, this opportunity is offered by the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), through the ERA system. The funding opportunity number is RFA CK 20 003, and the funding instrument is a Cooperative Agreement, which typically signals substantial programmatic involvement by the agency compared with a standard grant. It falls under the health funding activity category (CFDA 93.084). The award ceiling listed is $650,000, and the CDC anticipated making about four awards under this announcement. Eligible applicants span a broad range of organizations, including state, county, and local governments; public and state-controlled institutions of higher education; independent school districts; special district governments; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; and nonprofit organizations both with and without 501(c)(3) status, along with other eligible entities as described in the full eligibility guidance.
Key dates included a creation date of October 23, 2019, with an original application closing date of February 18, 2020, and electronic submissions due by 5:00 p.m. Eastern Time on the deadline date. Overall, MInD Healthcare is positioned as a targeted CDC investment in modeling methods and usable decision-support tools that can reduce the impact of HAIs and antimicrobial resistance by improving outbreak prediction, prevention planning, and evaluation of interventions across US healthcare settings.Apply for RFA CK 20 003
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Modeling Infectious Diseases in Healthcare Research Projects to Improve Prevention Research and Healthcare Delivery (MInD Healthcare)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on Oct 23, 2019.
- Applicants must submit their applications by Feb 18, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $650,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the MInD Healthcare funding opportunity?
Modeling Infectious Diseases in Healthcare Research Projects to Improve Prevention Research and Healthcare Delivery (MInD Healthcare) is a CDC funding opportunity focused on strengthening how the United States anticipates, understands, and prevents healthcare-associated infections (HAIs), including infections linked to antimicrobial resistance (AR). It supports research that builds and applies computational and mathematical models that realistically represent how HAI-causing pathogens spread within and across healthcare settings.
What is the main goal of MInD Healthcare?
The central goal is to fund innovative modeling research that is designed for real-world use, not just academic study. The models should be developed with practical end users in mind, such as researchers, policymakers, and public health professionals who need decision-support tools for prevention and response in healthcare environments.
Which federal agency is offering this opportunity?
This opportunity is offered by the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC).
What is the funding opportunity number?
The funding opportunity number is RFA CK 20 003.
What type of funding instrument is used?
The funding instrument is a Cooperative Agreement, which typically means substantial programmatic involvement by the agency compared with a standard grant.
What is the CFDA number and category?
The opportunity falls under the health funding activity category with CFDA 93.084.
How much funding is available per award?
The listed award ceiling is $650,000.
How many awards did CDC anticipate making?
CDC anticipated making about four awards under this announcement.
What kinds of research does the NOFO emphasize?
The NOFO emphasizes three main research aims: (1) developing and refining models of transmission dynamics for HAI-causing pathogens, including antimicrobial-resistant pathogens; (2) building predictive approaches to identify or forecast outbreaks and project trends in HAI burden; and (3) using models to evaluate intervention strategies so decision-makers can compare the likely effectiveness of prevention and control measures.
What does "modeling transmission dynamics" mean in this program?
It refers to building or improving models that capture how pathogens responsible for HAIs spread within and across healthcare environments. This can include spread inside a single facility or across networks of facilities where patient movement and shared resources influence transmission.
Which healthcare settings can be included in the modeling work?
The opportunity supports modeling across a variety of healthcare settings, including hospitals, long-term care facilities, outpatient settings, and networks of facilities.
Does the opportunity include antimicrobial resistance (AR) work?
Yes. The program specifically includes HAIs linked to antimicrobial resistance and supports modeling of both resistant and susceptible HAIs.
What kinds of predictive modeling activities are prioritized?
Predictive work can include identifying or forecasting outbreaks and projecting trends in the burden of HAIs over time. The description highlights data-informed approaches to anticipate where and when infections may surge and to estimate how the HAI landscape might change under different conditions.
What examples of "different conditions" are mentioned for projecting trends?
Examples include shifts in antibiotic use patterns and changes in infection control practices.
What kinds of interventions can models be used to evaluate under this opportunity?
Models can be used to evaluate intervention strategies such as infection prevention protocols, screening strategies, isolation approaches, environmental cleaning methods, antimicrobial stewardship interventions, and broader system-level policies.
Are models expected to be usable by practitioners and decision-makers?
Yes. A key expectation is that models move beyond academic exercises and are developed with practical end users in mind, including researchers, policymakers, and public health professionals.
What is a defining feature of MInD Healthcare beyond individual awards?
The program is designed to create a connected community of experts focused on HAI and AR modeling, building a network of leading modelers that can serve as a national resource for evidence-based policy development and respond to evolving public health needs, including emergencies in healthcare settings.
How will the funded community be used as a national resource?
Based on the description, the intent is to cultivate ongoing, coordinated modeling capacity that can be mobilized when new threats emerge or when urgent healthcare-related public health questions need rapid, evidence-based modeling support.
How are applications submitted?
Applications are submitted electronically through the ERA system.
What were the key dates listed for this opportunity?
The creation date was October 23, 2019. The original application closing date was February 18, 2020, with electronic submissions due by 5:00 p.m. Eastern Time on the deadline date.
Who is eligible to apply?
Eligible applicants include a broad range of organizations: state, county, and local governments; public and state-controlled institutions of higher education; independent school districts; special district governments; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; and nonprofit organizations both with and without 501(c)(3) status, along with other eligible entities as described in the full eligibility guidance.
Does eligibility include nonprofit organizations without 501(c)(3) status?
Yes. The eligibility list explicitly includes nonprofit organizations with and without 501(c)(3) status.
Does eligibility include tribal governments and tribal organizations?
Yes. The eligibility list includes federally recognized tribal governments and other tribal organizations.
Does the opportunity focus on single facilities or facility networks?
It includes both. The modeling scope can cover within-facility transmission and transmission across networks of facilities, including the effects of patient movement and shared resources.
What is the overall purpose of CDCs investment through this program?
Overall, MInD Healthcare is positioned as a targeted CDC investment in modeling methods and usable decision-support tools to reduce the impact of HAIs and antimicrobial resistance by improving outbreak prediction, prevention planning, and evaluation of interventions across U.S. healthcare settings.
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