Opportunity Information: Apply for RFA CK 20 003

Modeling Infectious Diseases in Healthcare Research Projects to Improve Prevention Research and Healthcare Delivery (MInD Healthcare) is a CDC funding opportunity designed to strengthen the way the United States anticipates, understands, and prevents healthcare-associated infections (HAIs), including infections linked to antimicrobial resistance (AR). The central goal is to fund innovative research that builds and applies computational and mathematical modeling approaches that can realistically represent how HAI-causing pathogens spread within and across healthcare settings. These models are expected to go beyond academic exercises by being developed with practical end users in mind, such as researchers, policymakers, and public health professionals who need reliable tools to guide decisions about prevention and response in real healthcare environments.

The NOFO emphasizes three main research aims. First, it supports the development and refinement of models that capture transmission dynamics of pathogens responsible for HAIs, including those that are antimicrobial resistant. This can include modeling spread within hospitals, long-term care facilities, outpatient settings, or networks of facilities where patient movement and shared resources can influence transmission. Second, it prioritizes predictive work that can identify or forecast outbreaks and project trends in the burden of both resistant and susceptible HAIs. In practice, this means using data-informed approaches to anticipate where and when infections may surge, and estimating how the overall HAI landscape might change under different conditions, such as shifts in antibiotic use patterns or infection control practices. Third, it funds studies that use models to evaluate intervention strategies, helping decision-makers compare the likely effectiveness of prevention and control measures, including infection prevention protocols, screening strategies, isolation approaches, environmental cleaning methods, antimicrobial stewardship interventions, or broader system-level policies.

A defining feature of MInD Healthcare is that it is structured to create a connected community of experts focused on HAI and AR modeling. The program is intended to build a network of leading modelers who can collectively serve as a national resource for evidence-based policy development and can also respond to evolving public health needs, including emergencies that arise in healthcare settings. In other words, the CDC is not only funding individual research projects, but also aiming to cultivate an ongoing, coordinated modeling capacity that can be mobilized when new threats or urgent questions emerge.

Administratively, this opportunity is offered by the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), through the ERA system. The funding opportunity number is RFA CK 20 003, and the funding instrument is a Cooperative Agreement, which typically signals substantial programmatic involvement by the agency compared with a standard grant. It falls under the health funding activity category (CFDA 93.084). The award ceiling listed is $650,000, and the CDC anticipated making about four awards under this announcement. Eligible applicants span a broad range of organizations, including state, county, and local governments; public and state-controlled institutions of higher education; independent school districts; special district governments; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; and nonprofit organizations both with and without 501(c)(3) status, along with other eligible entities as described in the full eligibility guidance.

Key dates included a creation date of October 23, 2019, with an original application closing date of February 18, 2020, and electronic submissions due by 5:00 p.m. Eastern Time on the deadline date. Overall, MInD Healthcare is positioned as a targeted CDC investment in modeling methods and usable decision-support tools that can reduce the impact of HAIs and antimicrobial resistance by improving outbreak prediction, prevention planning, and evaluation of interventions across US healthcare settings.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Modeling Infectious Diseases in Healthcare Research Projects to Improve Prevention Research and Healthcare Delivery (MInD Healthcare)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
  • This funding opportunity was created on Oct 23, 2019.
  • Applicants must submit their applications by Feb 18, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $650,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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