Opportunity Information: Apply for PAR 18 208
Bioengineering Research Partnerships (U01 Clinical Trial Optional), funding opportunity number PAR-18-208, is a National Institutes of Health (NIH) cooperative agreement program designed to speed up the development and real-world adoption of promising bioengineering tools and technologies that tackle significant biomedical problems. The central idea is to move beyond early prototypes and demonstrate that a technology is robust, reproducible, and well-characterized, so it can reliably fill an unmet need in biomedical research or clinical practice. NIH is looking for projects where the engineering is tightly connected to a clear biomedical use case, with measurable performance and validation that makes the resulting tool broadly credible and usable.
The program emphasizes multidisciplinary partnerships and an integrative, quantitative bioengineering approach. In practice, this means applications are expected to bring together engineers, computational or quantitative scientists, and biomedical researchers and/or clinicians in a way that is not superficial. Biomedical end users should be engaged throughout the project, helping define requirements, guiding design decisions, and participating in testing and evaluation. The intent is to reduce the common gap where a technology is impressive technically but not adopted because it does not fit real workflows, does not answer the right biological question, or lacks adequate validation in relevant settings.
A key feature is the timeline expectation: projects should be aimed at delivering meaningful, field-advancing solutions within roughly 5 to 10 years. This framing signals that NIH is looking for substantial development and maturation of technology, not incremental engineering or basic discovery alone. While the announcement is labeled “Clinical Trial Optional,” the mechanism allows clinical trial activities if they are appropriate for the tool being developed, but a clinical trial is not required for every project. As a U01 cooperative agreement, recipients should also expect a more collaborative relationship with NIH program staff than in a standard grant, with NIH having substantial involvement consistent with the cooperative agreement structure (for example, through milestone-oriented management or coordinated programmatic oversight).
Eligibility is broad and includes many types of U.S.-based organizations such as state, county, city, and special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; tribal organizations that are not federally recognized; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and non-U.S. entities (foreign organizations), reflecting NIH’s interest in reaching diverse institutional partners and settings.
From the source details provided, this FOA falls under the discretionary funding category and uses the cooperative agreement funding instrument. It is associated with multiple CFDA numbers (93.113, 93.273, 93.279, 93.286, 93.393, 93.394, 93.395, 93.399, 93.853, 93.865, 93.867), indicating that multiple NIH institutes and centers may participate or that the scientific scope spans several NIH program areas. The record indicates an original closing date of January 7, 2019, and a creation date of November 7, 2017. The award ceiling and expected number of awards were not specified in the provided excerpt, so applicants would typically need to consult the full FOA or NIH notices for budget guidance, project period limits, and any institute-specific participation details.Apply for PAR 18 208
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Bioengineering Research Partnerships (U01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.273, 93.279, 93.286, 93.393, 93.394, 93.395, 93.399, 93.853, 93.865, 93.867.
- This funding opportunity was created on 2017-11-07.
- Applicants must submit their applications by 2019-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (PAR 18 208) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) Apply for PA 18 488 Funding Number: PA 18 488 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54 Clinical Trial Optional) Apply for PAR 18 657 Funding Number: PAR 18 657 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $2,000,000 |
| Research on the Health of Transgender and Gender Nonconforming Populations (R21 Clinical Trial Optional) Apply for PA 18 728 Funding Number: PA 18 728 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Research on the Health of Transgender and Gender Nonconforming Populations (R01 Clinical Trial Optional) Apply for PA 18 729 Funding Number: PA 18 729 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) Apply for RFA NS 19 007 Funding Number: RFA NS 19 007 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00) Apply for RFA NS 19 011 Funding Number: RFA NS 19 011 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Restoring Research Resources Lost or Damaged Due to Hurricanes Harvey, Irma, and Maria (R24 Clinical Trial Optional) Apply for RFA OD 18 102 Funding Number: RFA OD 18 102 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trial Not Allowed) Apply for RFA OD 19 012 Funding Number: RFA OD 19 012 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 19 090 Funding Number: PA 19 090 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 - Independent Basic Experimental Studies with Humans Required) Apply for PA 19 089 Funding Number: PA 19 089 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 19 087 Funding Number: PA 19 087 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Basic Experimental Studies with Humans Required) Apply for PA 19 086 Funding Number: PA 19 086 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: NeuroImaging Tools and Resources Collaboratory (R24 Clinical Trial Not Allowed) Apply for RFA EB 18 004 Funding Number: RFA EB 18 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $600,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) (Collaborative R34- Clinical Trial Not Allowed) Apply for RFA DA 19 029 Funding Number: RFA DA 19 029 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 19 134 Funding Number: PAR 19 134 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $300,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) ( R34- Clinical Trial Not Allowed) Apply for RFA DA 19 036 Funding Number: RFA DA 19 036 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Limited Competition for a Connectome Coordination Facility (R24 Clinical Trial Not Allowed) Apply for RFA MH 20 210 Funding Number: RFA MH 20 210 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $900,000 |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 19 016 Funding Number: RFA OD 19 016 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trials Required) Apply for RFA OD 19 018 Funding Number: RFA OD 19 018 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 19 015 Funding Number: RFA OD 19 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
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