Opportunity Information: Apply for PAR 21 252
The Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed), PAR-21-252, is a National Institutes of Health (NIH) Fogarty program designed to help early-career scientists in low- and middle-income countries (LMICs) build strong, independent research careers. The core idea is to provide a substantial period of protected time and research support for three to five years so a junior faculty member can deepen their expertise, publish, develop leadership skills, and become competitive for independent funding while remaining based at an LMIC institution. The program emphasizes mentored career development, with guidance from both LMIC and U.S. mentors, and expects awardees to emerge as research leaders who continue contributing in their home institution or another LMIC setting.
A key boundary of this specific FOA is that the applicant cannot propose to lead an independent clinical trial. That includes not serving as the lead investigator for a clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. However, the award does allow the applicant to gain clinical trial experience if the trial is led by a mentor or co-mentor, meaning the candidate can still build relevant skills without being the person responsible for directing the trial. Applicants whose proposed research requires them to lead a clinical trial (or lead an ancillary clinical trial) are directed to apply to the companion FOA intended for those clinical trial leadership activities.
The opportunity is open to LMIC scientists from any health-related discipline, as long as the proposed research and career development plan align with the health priorities of the applicant's country. In practice, a strong application would typically combine a focused research project with a structured training and mentorship plan that clearly builds the applicant's trajectory toward independence. The expectation is that the mentored period is intensive and outcome-oriented, positioning the awardee to obtain future grants and sustain a productive research program.
Eligibility is restricted to non-U.S. (non-domestic) applicant institutions located in countries classified by the World Bank as low-income, lower-middle-income, or upper-middle-income. Only foreign institutions in these LMIC categories may apply as the applicant organization. Non-domestic components of U.S. organizations are explicitly not eligible to apply as the applicant institution. At the same time, foreign components as defined in the NIH Grants Policy Statement are allowed, which generally supports international collaboration structures while keeping the primary applicant organization in an eligible LMIC.
Administratively, this is a discretionary grant mechanism under NIH, aligned with health and related research and training activity areas, and associated with multiple CFDA (Assistance Listing) numbers including 93.113, 93.121, 93.172, 93.242, 93.398, 93.853, and 93.989. The FOA was created on 2021-09-08, and the listed original closing date is 2023-12-11. The provided source excerpt does not specify an award ceiling or the expected number of awards, so those details would need to be confirmed in the full FOA or related NIH documentation.Apply for PAR 21 252
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.242, 93.398, 93.853, 93.989.
- This funding opportunity was created on 2021-09-08.
- Applicants must submit their applications by 2023-12-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others.
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FAQs: Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed), PAR-21-252
What is the Emerging Global Leader Award (K43) opportunity?
The Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed), PAR-21-252, is an NIH Fogarty career development program intended to help early-career scientists based in low- and middle-income countries (LMICs) build strong, independent research careers. It supports a multi-year period of protected time and research support so candidates can deepen expertise, publish, develop leadership skills, and become competitive for future independent funding while remaining based at an LMIC institution.
Who is this program designed for?
It is designed for early-career scientists (for example, junior faculty) in LMICs who are seeking an intensive, mentored career development period to accelerate progress toward research independence and long-term leadership in their home institution or another LMIC setting.
What are the main goals of the award?
The stated goals include providing protected time and support for three to five years so the awardee can strengthen research skills, produce publications, develop leadership capabilities, and become competitive for independent research funding, with the expectation that the awardee will emerge as a research leader contributing in an LMIC setting.
How long is the supported period?
The program description indicates support for three to five years.
Where is the awardee expected to be based during the award?
The program is structured around the awardee remaining based at an LMIC institution, with the expectation that the awardee will continue contributing in their home institution or another LMIC setting.
What kind of mentorship structure does the program emphasize?
The program emphasizes mentored career development with guidance from both LMIC and U.S. mentors. A strong application is expected to combine a focused research project with a structured training and mentorship plan that builds the candidate's trajectory toward independence.
What disciplines are eligible to apply?
The opportunity is open to LMIC scientists from any health-related discipline, as long as the proposed research and career development plan align with the health priorities of the applicant's country.
What is the key clinical trial restriction in this FOA?
A key boundary is that the applicant cannot propose to lead an independent clinical trial. This includes not serving as the lead investigator for a clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial.
Can the candidate get clinical trial experience under this award?
Yes. The FOA allows the applicant to gain clinical trial experience if the trial is led by a mentor or co-mentor. In other words, the candidate can build clinical trial-related skills without being the person responsible for directing the trial.
What should applicants do if their research requires them to lead a clinical trial?
Applicants whose proposed research requires them to lead a clinical trial (or lead an ancillary clinical trial) are directed to apply to the companion FOA that is intended for clinical trial leadership activities.
What types of projects tend to fit this opportunity based on the description?
Based on the provided summary, a strong fit would typically include a focused research project paired with an intensive, outcome-oriented training and mentorship plan designed to move the candidate toward independence, publications, and competitiveness for future grant funding, while staying aligned with national health priorities in the applicant's country.
Which institutions are eligible to apply as the applicant organization?
Eligibility is restricted to non-U.S. (non-domestic) applicant institutions located in countries classified by the World Bank as low-income, lower-middle-income, or upper-middle-income. Only foreign institutions in these LMIC categories may apply as the applicant organization.
Are non-domestic components of U.S. organizations allowed to apply as the applicant institution?
No. Non-domestic components of U.S. organizations are explicitly not eligible to apply as the applicant institution.
Are foreign components allowed in the project?
Yes. Foreign components (as defined in the NIH Grants Policy Statement) are allowed, which supports international collaboration structures while keeping the primary applicant organization in an eligible LMIC.
Does the opportunity require alignment with country priorities?
Yes. The proposed research and career development plan are expected to align with the health priorities of the applicant's country.
What is the funding mechanism and administering agency?
This is a discretionary grant mechanism under the National Institutes of Health (NIH), specifically through the Fogarty program as described in the provided summary.
What Assistance Listing (CFDA) numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA (Assistance Listing) numbers, including 93.113, 93.121, 93.172, 93.242, 93.398, 93.853, and 93.989.
When was the FOA created and what is the listed closing date in the excerpt?
The FOA was created on 2021-09-08, and the listed original closing date in the provided excerpt is 2023-12-11.
Is the award ceiling or the expected number of awards provided in the excerpt?
No. The provided source excerpt does not specify an award ceiling or the expected number of awards. Those details would need to be confirmed in the full FOA or related NIH documentation.
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| Funding Opportunity |
|---|
| Emerging Global Leader Award (K43 Independent Clinical Trial Required) Apply for PAR 21 251 Funding Number: PAR 21 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01 Clinical Trial Optional) Apply for RFA ES 21 007 Funding Number: RFA ES 21 007 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $475,000 |
| Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed) Apply for PAR 22 072 Funding Number: PAR 22 072 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Emergency Award: Rapid Acceleration of Diagnostics Tribal Data Repository (RADx TDR) (U24 Clinical Trial Not Allowed) Apply for RFA OD 22 011 Funding Number: RFA OD 22 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| CCRP Initiative: Countermeasures Against Chemical Threats (CounterACT) Therapeutics Discovery and Early-Stage Development (UG3/UH3 Clinical Trial Not Allowed) Apply for PAR 22 209 Funding Number: PAR 22 209 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Multi-Omics for Health and Disease - Disease Study Sites (U01 Clinical Trial Optional) Apply for RFA HG 22 008 Funding Number: RFA HG 22 008 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 010 Funding Number: RFA HG 22 010 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $950,000 |
| Multi-Omics for Health and Disease - 'Omics Production Centers (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 009 Funding Number: RFA HG 22 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,700,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 22 028 Funding Number: RFA OD 22 028 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional) Apply for PAR 23 042 Funding Number: PAR 23 042 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Genomic Community Resources (U24 Clinical Trial Not Allowed) Apply for PAR 23 085 Funding Number: PAR 23 085 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 23 079 Funding Number: PAR 23 079 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 23 078 Funding Number: PAR 23 078 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 23 004 Funding Number: RFA ES 23 004 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed) Apply for PAR 23 109 Funding Number: PAR 23 109 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Translational Exploratory/Developmental Research Projects (R21 Clinical Trial Not Allowed) Apply for PAR 23 139 Funding Number: PAR 23 139 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $275,000 |
| Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Apply for RFA ES 23 001 Funding Number: RFA ES 23 001 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| STrengthening Research Opportunities for NIH Grants (STRONG): Structured Institutional Needs Assessment and Action Plan Development for Resource Limited Institutions (RLIs) (UC2 - Clinical Trial Not Allowed) Apply for PAR 23 144 Funding Number: PAR 23 144 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $250,000 |
| Tobacco Regulatory Science (R01 Clinical Trial Optional) Apply for RFA OD 23 017 Funding Number: RFA OD 23 017 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed) Apply for PAR 23 184 Funding Number: PAR 23 184 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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